Lichen simplex is an inflammatory skin condition that can affect different parts of the body. Commonly referred to as lichen skin, this dermatological disorder is often caused by repeated scratching that worsens the condition of the skin. Understanding its origin, symptoms and available treatment options helps ensure effective management. The Saint-Louis Research Center is interested in this topic as it regularly conducts dermatology clinical studies.
What is lichen skin or lichen simplex?
Chronic lichen simplex is a skin reaction to an irritating stimulus, creating a vicious cycle of itching and scratching. Unlike lichen planus or lichen sclerosus, it is not an autoimmune disease but rather an exaggerated skin response to prolonged irritation. This dermatological condition usually develops on areas that are easy to reach and scratch, such as:
The neck
The arms and forearms
The legs
The scalp
The genital and anal areas
Lichen simplex, the cause of lichen skin, is not contagious, but it can significantly affect quality of life due to the intensity of the itching and persistent skin lesions.
Lichen skin: causes and risk factors of lichen simplex
Lichen simplex is generally triggered by environmental and behavioral factors. The most common causes of lichen skin include:
Stress and anxiety: These psychological factors can worsen itching and lead to compulsive scratching.
Dry skin: Insufficiently hydrated skin is more prone to irritation and itching.
Allergies and irritants: Certain fabrics, soaps, fragrances or chemicals can irritate the skin and trigger inflammation.
Underlying dermatological conditions: Eczema, psoriasis and other inflammatory skin disorders can contribute to the development of lichen simplex.
Repeated scratching is both a cause and a consequence of lichen simplex, which worsens the condition and promotes its chronic progression.
Symptoms of lichen simplex
Lichen simplex is characterized by lichen skin appearing as well-defined, thickened patches caused by repeated scratching. The affected skin becomes rough and scaly, losing its natural softness and appearance. Itching, often intense, tends to worsen at night or during periods of stress, which fuels a vicious cycle of scratching and irritation. Over time, skin pigmentation may change, taking on red, brown or gray tones depending on skin type and disease progression.
Without treatment, lichen simplex can spread and become more difficult to control. Constant irritation of the skin may also lead to secondary infections that require medical care.
The Saint-Louis Research Center regularly conducts specialized dermatology clinical studies, including studies on lichen simplex. Consult the ongoing studies to learn about current research opportunities.


